Fletcher has been the frontwoman of an evolving series of pop groups from the 1980s to the present. Her bands included
Talulah Gosh,
Heavenly,
Marine Research,
Tender Trap, and, since 2014, The Catenary Wires. In 2020, she began a new band,
Swansea Sound, with
The Pooh Sticks's Hue Williams. She is associated with the
twee pop scene. In 2025, she released an album of song-poems as The Catenary Wires with poet
Brian Bilston. She also sang backing vocals for
The Wedding Present early in their career and on the
Hefner album
We Love the City. She toured with, and was guest vocalist for,
The Pooh Sticks on their albums
Orgasm,
Million Seller and
The Great White Wonder, and in 1988 released a single under her own name, "Can You Keep a Secret?" She has also appeared as a guest vocalist for
The 6ths on the song "Looking for Love (In the Hall of Mirrors)", on “Monday Morning” by
The Candyskins, on both
Bugbear recordings, a single by The Hit Parade, and on the "Why Do You Have to Go Out With Him When You Could Go Out With Me?" single by
The Brilliant Corners. From 1999 to 2003, she was keyboardist for
Sportique. Amelia Fletcher was also an early promoter of Scottish group
Bis who Heavenly performed alongside and whose lead singer, Manda Rin, repeatedly cited Amelia as one of her inspirations/influences. With husband and long-time musical collaborator, Rob Pursey, she co-founded independent label, Skep Wax Records. ==Economics career==