In 1981, it was demonstrated that the
gonadotropin-releasing hormone (GnRH) agonistic analogs that Schally had developed between the years of 1972 and 1978 inhibited the growth of prostate cancer in rats. Alongside Dr. George Tolis, Schally conducted the first clinical trial of GnRH for patients with advanced
prostate cancer in 1982. This method is now the preferred treatment for advanced prostate carcinoma. About 70% of patients with prostate cancer receive an agonist as their primary method of treatment. According to Schally, his treatment causes fewer side effects than radiation and
chemotherapy. The previous method of treatment,
orchiectomy or the administration of estrogens, was based on the research of
Charles Brenton Huggins. In 2004, after the death of his wife due to
thyroid cancer, Schally found comfort in continuing his research. ==Awards and honors==