Gupta is a faculty member at
Johns Hopkins University and previously served in clinical faculty and advisory roles at Drexel University and University of Pennsylvania. She has been a leading voice on issues related to pain management, opioid misuse, and drug policy. Gupta has advised federal agencies, including the
Food and Drug Administration, on expanding access to naloxone and combatting the synthetic opioid crisis. During the COVID-19 pandemic, Gupta was frequently cited as an expert on pain medicine, drugs, and public health. She appeared in major media outlets such as
The New York Times,
USA Today, and
WebMD, advising against the preemptive use of ibuprofen before COVID-19 vaccination and discussing long-term immunity and public safety protocols. She also contributed to public understanding of monoclonal antibody treatments and the flu-COVID coinfection risk. Gupta is a frequent contributor to healthcare policy and drug discussions, writing for platforms such as
Forbes and
FierceHealthcare on topics including sustainability in healthcare, drug, digital health transformation, and data analytics. She has published extensively in academic journals and contributed to books on anesthesia pharmacology and drugs. ==Honors and recognition==