Blume began an industrial career in 1996 as a chemist with the product development group at silica supplier Degussa AG (later to become Evonik). In 2011, she managed intellectual property for silica and silane in rubber applications. Blume's academic career began when she joined the University of Twente in 2013, as Chair of Elastomer Technology and Engineering (ETE) Group. She has been noted for her contributions to rubber technology aimed at reduction, in particular for automotive
lightweighting and for tire
rolling resistance reduction. She was invited to a jury that judged
Nokian Tyres sustainability innovation challenge. She also served on the panel that selected the Tire Technology International Awards for Innovation and Excellence. Blume was elected to serve as head of the German Rubber Society's western group, DKG West, for the term 2018–2021. ==Awards==