Konkle started her career working on student films while at the
New York University and in experimental theater. During the first decade of her career, she appeared in small roles in TV shows such as
New Girl,
Shameless and
Ramy. From 2015 to 2017, she appeared as Tara "TMI" Milly Izikoff on the main cast of
Rosewood. In 2019, Konkle co-created with
Maya Erskine and Sam Zvibleman
Hulu's original TV comedy series
PEN15. Konkle and Erskine star as 13-year-old semi-fictional versions of themselves as adults. The show received critical acclaim and for her work, she earned two
Primetime Emmy Awards nominations for
Outstanding Writing for a Comedy Series in 2019 and
Outstanding Comedy Series in 2021. ==Personal life==