She directed the Prairie Street Players in Rochester. She and her father wrote
Plays from American History. O'Ryan collaborated with
Helen Smith Woodruff,
Madelyn Sheppard, and
Annelu Burns on the 1922 musical,
Just Because. She wrote the book for the original version of the musical that was copyrighted in 1919. While the play was being readied for production in New York, O'Ryan rewrote parts of the book, and rewrote the comedy lyrics on behalf of the lyricist, Annelu Burns. After theater productions took place, the musical received praise. In 1925, O'Ryan married
Colonel James Crooke McLeer in New York City. About a year after their marriage, her husband died. Around July 14, 1928, Anna died with her mother in their home in New York, from
asphyxiation due to a gas stove. Their bodies were found about four days after their deaths by her brother. ==Selected works==