Known predators of the antelope jackrabbit include
bobcats,
coyotes, and
golden eagles. Since antelope jackrabbits attract predators that are also a threat to livestock, they are hunted by humans to reduce potential problems. This species is also hunted for human consumption or for their valuable pelt. The jackrabbits themselves were once so abundant as to be considered an agricultural pest on their own, but a 2018 account remarks that this has since become a rare occurrence. Live jackrabbits were historically used to train racing
greyhounds. Habitat loss also poses a threat to antelope jackrabbits, as
agricultural expansion is interfering with their habitats. Grazing livestock reduce the abundance of grasses and herbaceous plants in areas where antelope jackrabbits reside. As they naturally avoid wide open spaces, the expansion of croplands and pastures has the potential to eliminate populations of antelope jackrabbits. Disease, vehicle collisions, cold weather and predators all pose direct threats to the species. Antelope jackrabbits have few legal protections, being classified only as "wildlife" in both Arizona and Mexico. However, the subspecies
L. a. tiburonensis has a particularly small population, estimated at only 4,300 individuals across a habitable area of , and is isolated on the
protected area of
Tiburón Island. This subspecies is continually monitored and protected by the Mexican government. On a whole, the antelope jackrabbit is classified by the
International Union for Conservation of Nature as a
least-concern species. Research on the jackrabbit's population dynamics and the relationships between it and the
black-tailed jackrabbit has been recommended. ==See also==