The anterior nuclei receive
afferents from the
hippocampus and
subiculum directly via the
fornix, and indirectly via the
mammillary bodies and
mammillothalamic tract (MTT). They send efferent fibers to the
cingulate gyrus, limbic, and orbitofrontal cortex. The anterior nuclei of the thalamus display functions pertaining to memory. Persons displaying lesions in the anterior thalamus, preventing input from the pathway involving the hippocampus, mammillary bodies and the MTT, display forms of amnesia, supporting the anterior thalamus's involvement in episodic memory. However, although the hypothalamus projects to both the mammillary bodies and the anterior nuclei of the thalamus, the anterior nuclei receive input from hippocampal cells deep to the pyramidal cells projecting to the mammillary bodies. These nuclei are considered to be association nuclei, one of the three broader subdivisions of thalamic nuclei. These nuclei receive input from the
cerebral cortex. The input received is integrated and re-directed back to the cortical areas of the cerebrum known as association areas. The anterior nuclei regulate the input which is redistributed to the cortex. The connections of the anterior nuclei are similar to those of the lateral dorsal (LD) nuclei. ==Function==