Following the many suspensions handed out to Essendon players at the end of 2015 for the
supplements controversy fallout, McDonald-Tipungwuti was elevated to the Bombers' senior list. He made his
AFL debut in Round 1 of the
2016 season against the
Gold Coast Suns at
Metricon Stadium, and he retained his position in the team until his retirement. In July 2020, he broke the record for most consecutive AFL games for Essendon in the AFL era. His streak ended at 126 games when he decided not to play in Round 22, 2021, for personal reasons. McDonald-Tipungwuti has finished in the top 10 for the
Crichton Medal, Essendon's best-and-fairest award, each season of his career—5th in 2018; 7th in 2016, 2017, and 2020; 8th in 2019; and 10th in 2021 despite not playing in the club's final three games. He was also Essendon’s leading goalkicker in the shortened
2020 season, with 19 goals. McDonald-Tipungwuti announced his retirement on 20 May 2022; however, he revoked the announcement on 10 November 2022. After a comeback season in 2023, he announced his retirement for good on 24 August 2023, playing his last game, a loss against Collingwood, the following day. ==Statistics==