Marriage and issue , circa 1853 Maria Isabella married her uncle
Prince Francis, Count of Trapani, youngest son of
Francis I of the Two Sicilies and his wife
Maria Isabella of Spain, on 10 April 1850. Maria Isabella and Francis had six children: •
Princess Maria Antonietta of Bourbon-Two Sicilies (16 March 1851 – 12 September 1938) : ∞
Prince Alfonso, Count of Caserta on 8 June 1868 in
Rome, had 12 issue. • Prince Leopoldo Maria of Bourbon-Two Sicilies (24 September 1853 – 4 September 1870) • Princess Maria Teresa Pia of Bourbon-Two Sicilies (7 January 1855 – 1 September 1856) •
Princess Maria Carolina of Bourbon-Two Sicilies (21 February 1856 – 7 April 1941) : ∞
Count Andrzej Przemysław Zamoyski on 19 November 1885 in
Paris, had 7 children. • Prince Ferdinando Maria of Bourbon-Two Sicilies (25 May 1857 – 22 July 1859) • Princess Maria Annunziata of Bourbon-Two Sicilies (21 September 1858 – 20 March 1873)
Death On 14 July 1901, Maria Isabella died near
Lucerne,
Switzerland, at age 67. She was survived by two daughters. ==Honours==