Marie Anne was born on 8 June 1804 at the
Hofburg palace in
Vienna. She was the tenth child born to her parents, the Holy Roman Emperor
Francis II by his second wife,
Princess Maria Theresa of Naples and Sicily. In 1807, her mother died seven days after giving birth to her only younger sister, Archduchess Amalie Theresa, who died three days after being born. Like her eldest brother, Emperor
Ferdinand I, Marie Anne was intellectually disabled. She was born with a severe facial deformity, probably linked to the genetic inbreeding within her family; her parents were double first cousins. After living in the
Schönbrunn Palace, she was moved in 1835 to
Hetzendorf Palace, where she spent the rest of her life, and where she died on 28 December 1858 at the age of 54. Marie Anne was buried at the
Capuchin Church in Vienna, more specifically in the
Imperial Crypt, the burial place of her siblings
Marie Louise, Duchess of Parma,
Ferdinand I of Austria, Archduchess Marie Caroline,
Archduchess Caroline Ludovika of Austria,
Archduke Johann Nepomuk of Austria,
Archduchess Amalie Theresa of Austria, and
Archduke Franz Karl of Austria. Her parents, Francis II, Holy Roman Emperor and Maria Theresa of Naples and Sicily, and her great-grandmother,
Maria Theresa of Austria, are also buried there. ==Ancestry==