This gene encodes a member of the
Rho-GAP family of
GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive
GDP-bound state. It is implicated in regulating
adhesion of
hematopoietic cells to the
extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene. == References ==