Highway 146 was created by the
Arkansas State Highway Commission between January 1, 1932 and June 1933 as a route between
State Road 3 (now US 79) near Stuttgart through
Crocket's Bluff to
State Road 1 near
St. Charles. The route was truncated at Casscoe during an extension of Highway 33 on May 9, 1956, and the segment serving
Crocket's Bluff was redesignated as
Highway 153. A second segment of Highway 146 was created on June 23, 1965, designating a roadway located south of Holly Grove running east as a state highway. This route was extended to the Phillips County line on November 23, 1966. At the request of the Monroe
County Judge, the highway was extended west to Lawrenceville on April 27, 1971, in exchange for a truncation of
Highway 86 near Clarendon. The route was extended from the Phillips County line to Highway 39 at the request of the Phillips County Judge, in exchange for a truncation of
Highway 44 on May 14, 1980. ==Major intersections==