Early work and breakthrough (1950s–1970s) Villegas joined the Bogotá gallery El Callejón, where he worked in various capacities, including as a framer and curator. The exhibition advanced Colombian abstract art. In 1973, Villegas visited the
Dominican Republic on behalf of the
United Nations to promote the arts. The Caribbean influenced his palette and led to the development of his most recognized series, the "guerreros" (warriors), a shift after two decades of abstract work. These warrior figures became central to Villegas's artistic identity. The figures stand at the center of each painting, wearing elaborate and fantastical headdresses. Villegas painted them in dark, somber tones and surrounded them with plants and animals from across the Americas. The warriors face the viewer with expressions described as alternately naive and defiant. The warrior series was partly inspired by his second wife's surname, Sonia Guerrero Dah-Dah.
Later work and multimedia exploration Villegas continued to evolve artistically, returning to abstraction while simultaneously exploring sculpture. He created "soft sculptures" and collages using found objects from his studio and home, including soccer balls, jewelry cases, kitchen gloves, coins, fabric coats, used shoes, and discarded materials from his students. ==Cultural contributions==