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Arterial dissections

An arterial dissection is a tear within the wall of an artery, which allows blood to separate the wall layers. There are several types. Tears almost always occur in arterial walls, but a vein wall tear has been documented.

Description
Arterial dissections become life-threatening when growth of the false lumen prevents perfusion of the true lumen and the related end organs. For example, in an aortic dissection, if the left subclavian artery orifice were distal to the origin of the dissection, then the left subclavian would be said to be perfused by the false lumen, while the left common carotid (and its end organ, the left hemisphere of the brain) if proximal to the dissection, would be perfused by the true lumen proximal to the dissection. of an aortic dissection1 Aorta descendens with dissection2 Aorta isthmus Vessels and organs that are perfused from a false lumen may be well-perfused to varying degrees, from normal perfusion to no perfusion. In some cases, little to no end-organ damage or failure may be seen. Similarly, vessels and organs perfused from the true lumen but distal to the dissection may be perfused to varying degrees. In the above example, if the aortic dissection extended from proximal to the left subclavian artery takeoff to the mid descending aorta, the common iliac arteries would be perfused from the true lumen distal to the dissection but would be at risk for malperfusion due to occlusion of the true lumen of the aorta by the false lumen. == Types ==
Types
Examples include: • Aortic dissection (aorta) • Coronary artery dissection (coronary artery) also referred to as spontaneous coronary artery dissection or SCAD • Pulmonary artery dissection (pulmonary artery) an extremely rare condition as a complication of pulmonary hypertensionCarotid artery dissection (carotid artery) • Vertebral artery dissection (vertebral artery) Carotid and vertebral artery dissection are grouped together as "Cervical artery dissection" (CeAD). == Common features ==
Common features
As a disease family, arterial dissections share common features, including shared genetic risk variants, and commonly perturbed molecular pathways. ==References==
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