Williams began his career in private family practice. From July 1910 to 1914, Williams was engaged in private practice in Madison and Russell counties in Alabama. In early 1914, he joined Alabama State health Department as an epidemiologist. He served in that role for almost three years, resigning in October 1916 to prepare for examination for entrance into the
U.S. Public Health Service. On March 26, 1917, Williams was commissioned as an assistant surgeon in the regular
commissioned corps of the U.S. Public Health Service. From 1936 to 1942 he was assigned as chief medical officer of the
Farm Security Administration. In December, 1943, he was appointed Assistant Surgeon General of the U.S. Public Health Service, with rank of rear admiral, in charge of the
Bureau of Medical Services. In that position, he was in charge of all Public Health Service hospitals. Williams authored
The United States Public Health Service, 1798–1950, which was published in 1951, the year he retired from the Public Health Service. After retiring from the Public Health Service, Williams served for eight years as director of the Division of Hospital Services for the state of Georgia. He also taught hospital administration at the
University of Georgia campus in Atlanta. ==Fraternity leadership==