In the course of her career, Ghose served in Austria, the Netherlands, Bangladesh and the Permanent Mission of India in New York. She was also the key liaison to the Bangladesh Government in exile in Calcutta during the 1971 War. In 1996, Ghose was deputed to head India's delegation to the
CTBT conference in Geneva. India was a key participant at this conference, being one of only three countries that possessed nuclear technology and yet remained unrecognized as a nuclear power and outside the ambit of the
Nuclear Non-proliferation Treaty (NPT). In keeping with its long standing and oft-enunciated policy, India declined to endorse any regime that permitted some countries to retain nuclear weaponry while limiting the ability of other countries to develop similar capabilities of their own. She resisted pressure from the Western countries on India to sign the CTBT, attaining celebrity status in India in the process. She retired in November 1997. ==Post-retirement==