Feidon Argous Giannakouli joined Feidon Argous, the first
women's football team in her hometown, in 2012 when the club was founded. They competed against Agia Paraskevi in a
playoff match for promotion to the
Greek A Division. The game ended in a 1–1 draw and went into a
penalty shoot-out. Giannakouli saved Agia Paraskevi's final penalty, while her teammate,
Eirini Nefrou, scored and gave the win to Feidon. In the
Greek Women's Cup, Dimitra helped her team reach the final where they faced
PAOK. She played the full 90 minutes as her team lost 7–0. In the 2017/18 season, Feidon finished in last place and got relegated back to the second division with only 1 win and 83 goals conceded.
Atromitos She joined
Greek A Division side Atromitos Athens in the summer of 2018 and stayed for two seasons. They finished 4th in 2018/19 and 3rd in 2019/20.
Avantes Chalkidas She moved to
A Division club Avantes Chalkidas in 2021 and she helped them finish at the top of the second group, conceding only 6 goals in 16 matches. They did not manage to win the league though as they came third in the
playoffs round. Giannakouli won the
PSAP Best Female Goalkeeper award for her performance during the 2021/22 season. In July 2022, she renewed her contract with Avantes for the following season, but, due to problems with the administration, she and the rest of the team left the club.
Ergotelis Giannakouli joined
A Division club
Ergotelis in November 2022 and helped them finish at the top of the second group undefeated. In the
playoffs round, they came in second place after losing two matches against
PAOK and Trikala 2011. In total she made 16 appearances for the team.
Panathinaikos She joined newly promoted
A Division club
Panathinaikos on 19 July 2023. She kept 11 clean sheets in 17 appearances as they finished 3rd in the league and reached the quarterfinals of the
Greek Cup.
AEK On 5 July 2024, Dimitra joined
AEK.She was the first-choice goalkeeper as the team won the
2024–25 Greek A Division and the
2025 Greek Cup. She made 21 total appearances and kept 14 clean sheets, including a clean sheet in the cup final. ==International career==