Nawab Ayaz Khan Jogezai is a Pakistani politician from Northern Balochistan and is serving as the Pashtun Nawab. He became Nawab after the death of Nawab Taimoor Shah Khan Jogezai. While he was still alive, Nawab Taimoor Shah Khan Jogezai nominated Nawab Mohammad Ayaz Khan Jogezai as the next Nawab. He survived an assassination attempt at Killa Saifullah in 1988 but was seriously injured. On the request of the Chairman of Pashtunkhwa Milli Awami Party, Mahmood Khan Achakzai, he joined the party. He was elected as a member of the National Assembly of Pakistan for NA-200 (Zhob-cum-Killa Saifullah in 1993 till 1996. He also remained a member of the Senate of Pakistan from 2003 to 2009. He contested for PB-3 constituency in the 2013 Balochistan provincial election and was successful. He was appointed Provincial Minister of Balochistan for Public Health and Engineering Department in 2013 and remained in office till 2018.