2017: WTA Tour doubles debut Partnering
Ye Qiuyu, Guo made her
WTA Tour main-draw debut at the
2017 Tianjin Open, after defeating
Dalila Jakupović and
Nina Stojanović in qualifying.
2023: Maiden title, WTA 1000 doubles debut Guo won her first WTA Tour title at the
Guangzhou Open with
Jiang Xinyu. She also reached the final of the
2023 Ningbo Open with Jiang Xinyu. She received a wildcard for the WTA 1000
China Open in doubles with Jiang. She received a wildcard for the WTA 500
Zhengzhou Open in singles but lost to
Lucia Bronzetti. At the same tournament, she also received a wildcard into the doubles event with Jiang. She received another wildcard for the
Jiangxi Open where she lost to
Leylah Fernandez. At the same tournament, she reached the semifinals in doubles with Jiang.
2024: Two WTA titles, major debut, top 35 Following a fourth final at the
Thailand Open in Hia Hin, partnering with
Jiang Xinyu, and a first third-round showing on her debut at a major, at the
Australian Open, she reached the top 50 in the rankings on 5 February 2024, and a new career-high on 4 March 2024, at No. 35. In August, Guo won the
Monterrey Open doubles title with
Monica Niculescu beating
Giuliana Olmos and
Alexandra Panova in the final in the match tiebreaker. Partnering
Moyuka Uchijima, she won her third WTA Tour doubles title at the
2024 Jiangxi Open, defeating
Katarzyna Piter and
Fanny Stollár in the final.
2025: WTA 1000 singles win, two 500 titles & top 20 in doubles Partnering with
Alexandra Panova, Guo won the doubles title at the
Adelaide International, defeating
Beatriz Haddad Maia and
Laura Siegemund in the final, in straight sets. They were also champions at the
Bad Homburg Open, overcoming
Lyudmyla Kichenok and
Ellen Perez in the final which went to a deciding champions tiebreak. Ranked No. 259 she qualified to make her WTA main-draw singles debut at the
Canadian Open and defeated
Yulia Putintseva in the first round, before losing to second seed
Iga Świątek in her next match. Despite the defeat, Guo reached a new career-high of world No. 208 in the singles rankings after the tournament on 11 August 2025. Playing alongside Alexandra Panova, she was runner-up in the doubles at the
Cincinnati Open, losing to second seeds
Gabriela Dabrowski and
Erin Routliffe in the final. As a result, despite the loss she reached the top 20 in the WTA doubles rankings on 18 August 2025. ==WTA Tour finals==