DeSoto made her film debut in 1979 with
The In-Laws. In 1987, DeSoto appeared in the biographic film
La Bamba. In that film, she portrayed Connie Valenzuela, the mother of
Ritchie Valens, played by
Lou Diamond Phillips. The next year, DeSoto collaborated with Phillips again in the 1988 biopic
Stand and Deliver, where she portrayed Fabiola Escalante, the wife of
Jaime Escalante (
Edward James Olmos). Her performance garnered her an Independent Spirit Award for Best Supporting Female. In 1989, she played the wife of
Dustin Hoffman's character in
Family Business. That same year, she landed the principal role in
Face of the Enemy. She also played Azetbur in
Star Trek VI: The Undiscovered Country (1991). DeSoto portrayed Linda in
The 24 Hour Woman (1999). She has also acted in the soap opera,
The Bold and the Beautiful. DeSoto wrote and appeared in “A Woman in Progress/Canto de Oro, Cuento de Mujer” that was produced by the Intar Theater group in New York in 2005. ==Personal life==