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Aziz Sancar

Aziz Sancar is a Turkish-American molecular biologist specializing in DNA repair, cell cycle checkpoints, and circadian clock. In 2015, he was awarded the Nobel Prize in Chemistry along with Tomas Lindahl and Paul L. Modrich for their mechanistic studies of DNA repair. He has made contributions on photolyase and nucleotide excision repair in bacteria that have changed his field.

Early life
, Turkey Aziz Sancar was born on 8 September 1946 to a lower-middle-class family in the Savur district of Mardin Province, southeastern Turkey. His oldest brother Kenan Sancar is a retired brigadier general in the Turkish Armed Forces. He is the second cousin of the politician Mithat Sancar, who is a member of parliament from and chairman of HDP. He is the seventh of eight children. He was educated by idealistic teachers who received their education in the Village Institutes, he later stated that this was a great inspiration to him. Throughout his school life, Sancar had great academic success that was noted by his teachers. He wanted to study chemistry whilst at high school, but was persuaded to study medicine after five of his classmates also got into medicine along with him. As such, he studied medicine at the Faculty of Medicine of Istanbul University. However, when asked about his origins, Sancar only underlined his Turkish nationality. Still, his cousin, Mithat Sancar, mentioned that their family is of Arab origins. Aziz Sancar's brother Tahir claimed in an interview that their family descended from Oghuz Turks from Central Asia, also mentioning that they are idealists. During his years at Istanbul University, he was involved with the Turkish nationalist organization Idealist Hearths (Ülkü Ocakları). == Education ==
Education
Sancar received his primary education near his hometown of Savur. in the laboratory of Claud Stan Rupert, now Professor Emeritus. == Career ==
Career
Sancar is an honorary member of the Turkish Academy of Sciences and the American Academy of Arts and Sciences. After graduating from Istanbul University, Sancar returned to Savur. Although he wanted to go to the United States, he was recommended to try out being a doctor, and he worked as a doctor in the region for 1.5 years. He then won a scholarship from TÜBİTAK to pursue further education in biochemistry at Johns Hopkins University, but returned to Savur in 1973 as a doctor after spending 1.5 years there due to having social difficulties and inability to adapt to the American way of life. He only spoke French when he arrived in the US, but learned English during his education at Johns Hopkins. After completing his PhD, Sancar had three rejected applications for postdoctoral positions and then took up work at Yale University as a laboratory technician. based on 1QNF Aziz Sancar was elected to the National Academy of Sciences in 2005 as the first Turkish member. Together, they founded Carolina Türk Evi, a permanent Turkish Center in close proximity to the campus of UNC-CH, which provides graduate housing for four Turkish researchers at UNC-CH, short term guest services for Turkish visiting scholars, and a center for promoting Turkish-American interchange. ==Research on circadian clock==
Research on circadian clock
Sancar and his research team have discovered that two genes, Period and Cryptochrome, keep the circadian clocks of all human cells in proper rhythm, syncing them to the 24 hours of the day and seasons. Their findings were published in the Genes and Development journal on September 16, 2014. Sancar's research has provided a complete understanding of the workings of Circadian clocks in humans, which may be used to treat a wide range of different illnesses and disorders such as jet-lag and seasonal affective disorder, and may be useful in controlling and optimizing various cancer treatments. ==Personal life==
Personal life
Sancar is married to Gwen Boles Sancar, with whom he met during his PhD in Dallas, where she was also studying molecular biology. They got married in 1978. Sancar is a practicing Muslim. In an interview, he stated: "I am proud to be Muslim, but I can not state this fact in many regions of the United States due to ongoing issues." In the immediate aftermath of being awarded the Nobel Prize, his ethnicity was questioned in social media. Sancar said he was "disturbed by some of the questions he received," particularly by questions about his ethnic background. When asked as to whether he is "a Turk or half-Arab" by the BBC, Aziz Sancar responded: "I told them that I neither speak Arabic nor Kurdish and that I was a Turk," he said. "I'm a Turk, that's it." Aziz Sancar's brother Tahir informed in an interview that their family descended from Oghuz Turks who once migrated from Central Asia. He also said that his brother's Nobel Prize was an honor for all of Turkey, including the Kurds. In an interview, Sancar stated that in his youth, he was an idealist but he didn't participate in activities. In another interview, Sancar stated that he supports moderate Pan-Turkism. On September 26, 2021, Sancar was the honorary guest of the Turkic Council on occasion of the meeting of the foreign secretaries from member states and has given a presentation titled "Knowledge and the National Awakening of the Turkic World", as announced by Turkish Minister of Foreign Affairs Mevlüt Çavuşoğlu. On 31 July 2025, Sancar was granted neutralized citizenship of the Turkish Republic of Northern Cyprus. == Awards ==
Awards
He was awarded the 2015 Nobel Prize in Chemistry along with Tomas Lindahl and Paul L. Modrich for their mechanistic studies of DNA repair. Sancar is the second Turkish Nobel laureate after Orhan Pamuk, who is also an alumnus of Istanbul University. Aziz Sancar donated his original Nobel Prize golden medal and certificate to the mausoleum of Mustafa Kemal Atatürk, with a presidential ceremony on 19 May 2016, which is the 97th anniversary of Atatürk initiating the Turkish War of Independence. He delivered a replica of his Nobel medal and certificate to Istanbul University, from which he earned his MD. On January 19, 2025, during a ceremony held at the Sancar Cultural Center in the state of North Carolina, USA, TÜRKSOY General Secretary Sultan Raev presented Sancar with the Order of Cultural Ambassador of the Turkic World. ==References==
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