Passenger services Bad Wimpfen is located on the Elsenz Valley Railway, running from Heilbronn via Sinsheim to Heidelberg. The railway line was extensively renovated from 7 January 2014 to the end of April 2015 and reopened on 1 May 2015. During this period, replacement buses ran between Sinsheim, Bad Rappenau and
Neckarsulm. Services of the RE 2 line of DB Regio (since December 2019 operated as RE 10b of Abellio BW) has been running between Mannheim, Heidelberg, Sinsheim and Heilbronn and line S 42 of the
Heilbronn Stadtbahn have run between Sinsheim, Bad Rappenau, Bad Wimpfen, Bad Friedrichshall, Neckarsulm and Heilbronn since May 2015. These have been operated by
SWEG Südwestdeutsche Landesverkehrs since January 2022, as a result of the insolvency of Abellio BW. Until early January 2014,
Regionalbahn service RB 74 ran hourly between Sinsheim, Bad Rappenau, Bad Wimpfen and Bad Friedrichshall (some to/from Heilbronn) and
Regional-Express service RE 2 ran between Mannheim, Heidelberg, Sinsheim and Heilbronn every two hours. The two services were operated with
class 425 EMUs.
Freight traffic A freight train runs regularly from Heilbron to the
Solvay chemical plant in Bad Wimpfen.{{cite web|url=http://www.cargonautus.de/KBS780.htm |title= Güterzugfahrzeiten der KBS 780 Konrwestheim - Heilbronn – Lauda - Würzburg == Bad Wimpfen Im Tal station==