Early career and Telecinco (1987–2004) Domínguez began her journalism career in 1987 at the news department of Radio España. She later worked at Efe Radio, the radio division of the
EFE news agency, and at
Canal+. In 1991, she joined
Telecinco, where she spent thirteen years working as a reporter, presenter, and editor across various news programmes. From January 2001 to June 2004, she directed and presented the morning political talk show
La mirada crítica, which featured interviews and debates with leading Spanish political figures. On 11 March 2004, she anchored Telecinco's live coverage of the
2004 Madrid train bombings, broadcasting for several hours as events unfolded.
Antena 3 (2004–2007) In June 2004, Domínguez left Telecinco and joined
Antena 3, where she directed and presented
Ruedo ibérico, a morning political discussion programme, together with the station's morning news edition. The programme aired until December 2006, when it was replaced by the daily edition of
Espejo público presented by
Susanna Griso.
Cadena SER and A vivir que son dos días (2007–2012) In September 2007, Domínguez joined
Cadena SER as a special contributor. In November 2007, she was appointed director and presenter of
A vivir que son dos días, the station's flagship weekend magazine programme, replacing
Àngels Barceló, who had moved to lead
Hora 25. She led the programme from January 2008 until May 2012, during which time it maintained its position as the audience leader in its time slot.
El HuffPost España (2012–2018) In March 2012, Domínguez was named founding editor of
El HuffPost (the Spanish edition of
HuffPost), a joint venture between
Prisa Noticias and The Huffington Post Media Group. She directed the digital publication for six years, until June 2018. During this period, she also contributed as a regular panellist on
El programa de Ana Rosa on Telecinco and on
La Ventana on Cadena SER.
El País (2018–2021) In June 2018, Domínguez was appointed deputy editor of
El País, where she oversaw the weekend edition,
El País Semanal, and coordinated the newspaper's magazine supplements, including
S Moda,
Icon,
Buena Vida,
Retina, and
Ideas.
Cadena SER content director (2021–2025) In May 2021,
Prisa Media appointed Domínguez as content director of
Cadena SER, Spain's most listened-to radio network, as part of a broader restructuring of the company's radio division under new CEO Carlos Núñez. In this role, she coordinated the station's news, programming, and sports departments. In May 2025, she was replaced by Fran Llorente, the former head of news at
RTVE, as part of a restructuring ordered by Prisa president Joseph Oughourlian following the appointment of Pilar Gil as CEO of Prisa Media. Llorente assumed a newly created position titled Director of Editorial and Content for Radio and Audiovisual Business, while Jaume Serra was named general director of the radio division for Spain. == Awards and recognition ==