"The Last Arkham" begins with the destruction of the old
Arkham Asylum at the hands of its new administrator,
Jeremiah Arkham, who inherited it from his deceased uncle,
Amadeus Arkham. The asylum is revamped and fitted with numerous new security measures. When Batman stumbles upon a series of murders, resembling the serial killer
Victor Zsasz's
MO, Batman begins to investigate only to find Zsasz has been imprisoned in Arkham Asylum during the course of the murders. Determined to prove Zsasz guilty, Batman and
Commissioner Gordon stage Batman's insanity in order to get him committed to Arkham and further investigate. However, Jeremiah Arkham is unaware of this plot and begins to break down Batman mentally and physically. Learning of Batman's incarceration through private talk with Jeremiah, Zsasz guesses Batman's insanity is obviously a ploy and begins to plant seeds of hatred towards Batman in Jeremiah's mind. This explodes when Jeremiah forces Batman to fight
Amygdala and other inmates from the asylum, including the
Joker, the
Mad Hatter, and
Egghead. Whilst this continues, Zsasz escapes through the tunnels which he had purchased and kills the builder and another inmate in order to cover his tracks. Batman defeats all the inmates and begins to wonder about Jeremiah Arkham's sanity, as Amadeus Arkham was in fact the asylum's first inmate. ==Character introductions==