Akhmedov made his professional debut on 23 February 2017, scoring a third-round
technical knockout (TKO) over Dmitry Lavrinenko at the Forum in
Nizhny Tagil, Russia. After compiling a record of 7–0 (6 KOs) he faced
Mario Barrios for the vacant
WBA (Regular) super-lightweight title on 28 September 2019 at the
Staples Center in
Los Angeles,
California. In a fight which saw Akhmedov have a knockdown scored against him after his gloves touched the canvas in the fourth round and a second knockdown in the twelfth and final round, Akhmedov lost via
unanimous decision (UD), a decision which many described as controversial. Judge Jeremy Hayes scored the bout 116–111, judge Tim Cheatham scored it 115–111, and judge Zachary Young scored it 114–112. Almost three years later, Akhmedov would challenge again for a vacant super-lightweight world title, this time the full WBA title against undefeated
Alberto Puello on 20 August 2022. Puello won the fight by
split decision. Two judges scored the fight 117–111 for Puello, while the third judge scored the fight 115–113. ==Professional boxing record==