Brown University Following her residency and fellowship, Borrelli joined the faculty at
Brown University in 1997. During her tenure at Brown, Borrelli led the first study focusing on Latino smokers who are caregivers to children with asthma. She also led the Parents of Asthmatics Quit Smoking project in 2002 which focused on how to motivate parents of kids with asthma to stop smoking. She served as the Co-Principal Investigator with Michelle Henshaw on a project aimed at motivating low income parents to engage in pediatric oral health behaviors, with the goal of cavity prevention. As a result of her research, Borrelli was promoted to the rank of full professor in 2009. Upon returning to the United States, she became the director of
Boston University's the Center for Behavioral Science Research and professor in the
Henry M. Goldman School of Dental Medicine's Department of Health Policy and Health Services Research in September 2014. In May 2017, Borrelli and colleagues from across Boston University launched an Affinity Research Collaborative on Mobile and Electronic Health. The aim of Mobile and Electronic Health ARC was to conduct research and training in mobile and electronic health to improve the health of populations, through mobile technology. As a result of her collaborative research, Borrelli was the recipient of the 2017 Evans Center Research Collaborator of the Year by the Evans Center for Interdisciplinary Biomedical Research and the Boston University Department of Medicine. During the
COVID-19 pandemic, Borrelli joined BU's Institute for Health System Innovation & Policy as their Director of the Digital Health Domain. She also became an associate editor of the journal
American Psychologist. ==Personal life==