MarketBenign acute childhood myositis
Company Profile

Benign acute childhood myositis

Benign acute childhood myositis (BACM) is a syndrome characterized by muscle weakness and pain in the lower limbs that develop in children after a recent viral illness. It is transient with a spontaneous clinical resolution within 1 week.

Symptoms
Prodromal symptoms are typically fever, cough, and rhinorrhea. BACM symptoms that follow are most frequently calf pain, gait complaints, and inability to walk. ==Diagnosis==
Diagnosis
The history of a preceding influenza-like infection followed by the typical symptoms of acute onset of symmetrical calf pain and gait problems together with an isolated finding of a high level of creatine kinase suggests the diagnosis of BACM. Myoglobinuria is rare and points to the possibility of the development of rhabdomyolysis and kidney failure. Guillain-Barré syndrome (GBS) is the main consideration in the differential diagnosis. It needs to be quickly excluded as early intervention in GBS is indicated. Other conditions under possible consideration are dermatomyositis, muscular dystrophy, juvenile idiopathic arthritis, transient synovitis of the hip, osteomyelitis, and myalgia. Few muscle biopsies have been conducted. Results may show normal findings or features of inflammation and necrosis. ==Preceding viral infections==
Preceding viral infections
A number of different preceding viral infections have been reported, most commonly influenza A and B. The condition appears to be more prevalent during late fall, winter, and spring. ==Management==
Management
BACM may be alarming to parents and lead to unnecessary extensive tests. Treatment consists of oral analgesics, rest, and adequate hydration. Hospitalization is usually not necessary. Full recovery can be expected within a week, however, recurrences can occur. ==History==
History
in 1957 Lundberg reported on a group of patients with a condition he named myalgia cruris epidemica, seemingly the first description of BACM. Other terms later used include influenza-associated myositis, viral myositis, acute myositis Viral myositis may occur also in later years. ==References==
tickerdossier.comtickerdossier.substack.com