Born in
Chicago, Illinois, on April 25, 1939, Hollander was the daughter of Shirley Mazur Garrison and Henry Garrison, a labor activist and member of the carpenters union. During the 1970s, she was the graphic designer of a
feminist publication,
The Spokeswoman, where she had the opportunity to transform the newsletter into a monthly magazine. While designing pages, she occasionally added her own political illustrations. Around 1978, she created a comic strip,
The Feminist Funnies, later introducing the character who became Sylvia. Selections from
The Feminist Funnies appeared as a calendar,
Witches, Pigs and Fairy Godmothers: The 1978 Feminist Funnies Appointment Calendar, and in her 1979 book, ''I'm in Training to Be Tall and Blonde''. The book's success led
Field Newspaper Syndicate to distribute
Sylvia to newspapers as a daily
comic strip starting in 1981. Hollander donated the archive of her work to the
Billy Ireland Cartoon Library & Museum at
Ohio State University. A number of her drawings are in the collection of the
Library of Congress. She was a faculty member at the
School of the Art Institute of Chicago, in 2011 offering a course in writing the
graphic novel. She led workshops and taught at
Ohio State University,
Columbia College Chicago, the Ox-Bow School of Art, Chicago's Printers Row Lit Fest, and for the Chicago Arts Partnership in Education. Her frequent appearances as a public speaker since 2001 have occurred at
The New School,
Loyola University Chicago,
DePaul University, the
Art Institute of Chicago,
Enoch Pratt Free Library, the
Library of Congress, Stagebridge, and elsewhere. In 2009, Hollander curated a show of women's humor,
And You Think This Is Funny?, for Chicago's Woman Made Gallery; the show included the work of some 50 women artists. The gallery's simultaneous ten-year retrospective exhibit of Hollander's work was titled ''It's Enough to Make a Cat Laugh.'' In 2012, Nicole Hollander's "unique collection of condom packages and sex toys" entered the collection of the
Kinsey Institute for Research in Sex, Gender, and Reproduction. In 2005, Hollander appeared in a one-woman show,
Return to Lust, at Pegasus Players in Chicago. A second show,
Plastic Surgery or a Real Good Haircut, opened in 2008 at Chicago's Live Bait Theatre. In these performances, she described her experiences as an aging woman dealing with physical vanity, sexual desire and an overlong birthday-party guest list. In 2013, the Lillstreet Gallery replicated Hollander's living room for an exhibit they called "Will You Step Into My Parlour?" == Retirement and death ==