Vallee was born in Hemer, Westphalia, Germany, to Josef and Rosa Blumenthal. The family moved to Luxembourg, where he completed his school education. He then moved to Switzerland to study science at the University of Bern. He earned his B.Sc. in zoology 1938. His course in developmental biology under Hans Spemann (laureate of the 1935
Nobel Prize in Physiology or Medicine for the discovery of
embryonic induction) would be a major influence in his later research. As soon as he graduated, he was selected for fellowship under the International Student Service of the
League of Nations by which he chose to study in US. He became the first and only fellow of this organisation. Under the tutorage and advice from Richard Courant, a Jewish mathematician at the
University of Göttingen who had fled Nazi Germany and joined the
New York University in 1936, Vallee qualified the entrance to medical course at the medical school of New York University. He received his M.D degree in 1943 and interned at
Glady Hospital in Atlanta and then at
Mount Sinai Hospital in New York City. Many scientists he worked with were Jewish refugees from Germany and Austria who influenced him on protein chemistry. After his intern, he briefly worked at Massachusetts Institute of Technology while also joining Harvard Medical School in Medicine and Biochemistry. At Harvard, he worked with two eminent protein scientists, Edwin Joseph Cohn and John Edsall, who initiated his research on blood proteins, particularly on the mystery at the time that zinc might be associated with white blood cells. a field he is credited with establishing and for which he received the Raulin Award. His work on alcohol
dehydrogenase, a zinc enzyme, led to his interest in the study of the molecular basis of alcohol use and abuse. Dr. Vallee was an expert on emission spectroscopy and the author of more than 600 scientific publications including books. He was an Honorary Professor of
Tsinghua University, Beijing, China, the
Shanghai Institute of Biochemistry, the
Chinese Academy of Sciences,
Shanghai, China, and the
Stellenbosch University, Stellenbosch, South Africa. He was a member of the National Academy of Sciences of the US and of the Royal Danish Academy of Science and Letters. Vallee held Honorary Degrees from the
Karolinska Institute, Stockholm, the
University of Naples Federico II, Naples, and
LMU Munich. == Awards and recognitions ==