The museum was initially opened on the ground floor of the old Fix Brewery in Athens, with approximately 1800 square meters of space. Ownership of the Fix building was transferred from the subway authority
Attica Metro, which owned the former brewery since the 1990s, to the museum foundation. The museum is located near the center of Athens as well as its primary archaeological sites, including the Acropolis and the
Acropolis Museum. As of 2020, the building is being restored to create state-of-the-art facilities for the permanent collection, periodic exhibitions, educational programs, and workshops. 3SK Stylianidis Architects won an international competition to complete the renovation of the Fix Building, in collaboration with Ioannis Mouzakis and Associates and others. While renovations are underway, EMST displays its exhibitions in parts of the Athens Conservatory. The Greek government has spent 40 million euros on the museum by 2020, with the
Stavros Niarchos Foundation giving a further 3 million euros. The delays in the museum's opening cost EMST a 3.3 million dollar subsidy from the
European Union.
Directors • Anna Kafetsi (2000-2014), Founding Director • Katerina Koskina (2014-2018) • Dimitris Antonakakis & Syrago Tsiara (2019-2021) Interim Directors • Katerina Gregos (2021-present) ==Collections==