Upon completing her formal education, Weinstock-Guttman accepted a faculty position at
University of Buffalo in 1998. In 2006, she helped establish the Pediatric MS Center of Buffalo with a grant from the
National Multiple Sclerosis Society. In 2017, Weinstock-Guttman was named the
principal investigator to lead clinical trials exploring potential therapeutic applications of cannabinoids in progressive multiple sclerosis. The following year, she received the
National Multiple Sclerosis Society's Impact Award for her research, patient care and advocacy skills. During the
COVID-19 pandemic, Weinstock-Guttman co-authored
Asymptomatic infection after BNT162b2 mRNA COVID-19 vaccination in multiple sclerosis patient with
Dejan Jakimovski. She was also the recipient of the 2020 Stockton Kimball Award for outstanding scientific achievement and service. The following year, she was promoted to the rank of SUNY Distinguished Professor, the highest rank in the SUNY system. ==References==