Bisacodyl

Bisacodyl is used to treat both episodic and chronic constipation, manage symptoms of neurogenic bowel dysfunction, as well as for bowel preparation for a colonoscopy. as well as being available generically. It is usually sold as 5 mg tablets, 10 mg suppositories, or 5 mg pediatric suppositories. It is also available as a pre-packaged enema containing a 10 mg delivered dose of liquid bisacodyl. Administration When administered rectally in suppository form, it is usually effective in 15 to 60 minutes. For optimal use, if used as a suppository, it is recommended that bisacodyl be given after breakfast to synchronize with the gastrocolic reflex. As a commercially prepared micro-enema, it is usually effective in 5 to 20 minutes. ==Mechanism of action==

Bisacodyl works by stimulating enteric neurons to cause peristalsis (i.e., colonic contractions). It is also a contact laxative; it increases fluid and salt secretion. The action of bisacodyl on the small intestine is negligible; stimulant laxatives mainly promote evacuation of the colon. == References ==