Main •
Kirk "Sticky Fingaz" Jones as
Eric Brooks / Blade • Jon Kent Ethridge as young Eric Brooks •
Jill Wagner as Krista Starr •
Nelson Lee as Shen, Blade's weaponsmith and electronics expert, who hacks computer networks for information on vampires and their business. He makes Blade's serum for him, and can speak and read the vampire language. Blade is helping him track down the vampires who killed his sister. •
Jessica Gower as Chase •
Neil Jackson as Marcus van Sciver
Recurring Humans •
Colin Lawrence as Robert Brooks (younger), the father of Eric Brooks (who becomes Blade). Robert's wife
Vanessa having been attacked by the vampire
Deacon Frost, Eric was subsequently born
half human, half vampire. In flashback scenes, Robert tries to take care of Eric despite problems caused by his craving for blood. Eventually, Eric runs away when he thinks Robert has betrayed him. •
Richard Roundtree as Robert Brooks (older). When Blade encounters Robert years later, the father tries to make amends for the past, but Blade coldly rejects him. •
Larry Poindexter as Agent Collins, an FBI agent whose family was killed by a serial killer. Initially investigating a series of killings linked to Detective Boone, he becomes aware of the links to vampires. •
Ryan Kennedy as Cain, a former familiar now the most powerful ash dealer in Detroit. His knowledge of the vampire world has allowed him to build a drug empire and make a lot of money selling vampire ash. •
Randy Quaid (uncredited) as Professor Caylo, a disgraced professor whom Krista Starr seeks out while investigating her brother's death. It is Caylo who explains to her that her brother was a familiar from the House of Chthon. He also gives her information about the vampire hunter Blade. • William MacDonald as Reverend Carlyle, an excommunicated priest who runs a small street ministry catering to drug addicts. Blade goes to him for information, and "donates" money he took from an ash dealer. He betrays Blade to the Bad Bloods, but is himself killed when they no longer need him. •
Elias Toufexis as Officer Donny Flannigan (younger), a police officer in Eric's (the young Blade's) neighborhood, who would find Eric when the boy ran away, and return him to his father. It was Flannigan who introduced Eric's father to
Abraham Whistler, who tested the boy. Flannigan helped cover up Eric's killing of the robbers in Mr. Taka's store. • Peter Hall as Donny Flannigan (older). Flannigan is killed years later by Steppin' Razor, who is tracking down and killing people from Blade's youth. He is killed in the same manner as one of the robbers. •
Hiro Kanagawa as Mr. Taka, a grocery store owner in Eric's (the young Blade's) neighborhood. Eric would sneak out of his locked bedroom to play chess with Mr. Taka in the park. When Eric ran away from home for good, he went first to Mr. Taka's store, but there interrupted a robbery. Mr. Taka was wounded by the robbers, and Eric's father shot. Enraged, Blade attacked and killed the robbers, before running away for good. In the main narrative, Steppin' Razor kills Mr. Taka after killing Donny Flannigan. •
Tom Butler as Tucker Moffet, an architect and vampire familiar whom Marcus hires to remodel the site of the pureblood conclave to make it ready for dispersal of the Aurora Virus. • Don Thompson as (Krista Starr's) Uncle Pat. It is Uncle Pat who tells her that her mom is dying. He is killed by Krista's mom after Krista has turned her. •
Sonja Bennett as Vanessa, a young woman approached by Dr. Vonner, ostensibly to serve as a surrogate mother for someone unable to have children. In fact she is incubating the Aurora Virus in her womb. Blade kidnaps her and takes her to a doctor in Paris who removes the virus, rendering her infertile. She is smuggled underground and disappears. • Andrew McIlroy as Doctor Vonner, an obstetrician hired by Marcus to help engineer the Aurora Virus. He selects young women to implant with a virus incubator instead of an embryo. He had also ran the test lab where Armayan vampires were tortured and experimented on. He commits suicide to avoid being captured by Blade. • David Kopp as Zach Starr, Krista Starr's recently dead brother. He had been a familiar to Marcus and also worked as a double agent for Blade. Marcus became aware of Zach's betrayal and lured him into a meeting at the docks. Tricked into thinking he was finally going to be turned into a vampire, he was instead shot in the head and his body dumped. Zach appears in Krista's visions, encouraging her to continue his work with Blade. • Robinne Fanfair as Viola Watkins (younger), a nurse who had once dated Eric's father, Robert. She helped him obtain blood to feed Eric's thirst, sometimes by tapping Robert's own blood. • BJ Harrison as Viola Watkins (older) Years later, she is hunted down by Steppin' Razor, who is killing people from Blade's past in order to lure him out. Blade and Shen narrowly save her from drowning, and she tells Blade that his father is still alive and is looking for him.
Vampires •
Bill Mondy as Detective Brian Boone, a familiar to Marcus. A police officer, he uses his influence to help the vampires cover up their crimes and to secure fresh humans for feeding. He is double-crossed by Marcus and fed to the newly turned Krista Starr, who inadvertently turns him. He escapes and goes on a cross-country killing spree that ends when a group from Chthon ambushes him at a meeting with the House of Armaya. Chase believes she has killed him; in fact he has survived, but is not heard from again. •
Kavan Smith as Alex, a pureblood from the House of Erebus. He is infatuated with Chase, having once been stood up by her. Chase spends a night with him in Las Vegas, but it is a ploy to lure him to Detroit. There, he is subjected to the Aurora Virus, dying in a successful test of its effect on a pureblood. •
David Palffy as Fritz, a vampire who is physically imposing and strong and does Marcus' muscle work. He begs to be a test subject for Aurora, and is injected with the vaccine, gaining immunity to garlic, silver, and sunlight. To test his new power, he engages Blade in a fight, which ends in a draw. Marcus orders him to Prague to display his new talents for the Chthon board of directors. On his way, he is distracted by Blade and goes to fight him. This time, Blade gets the upper hand, and is about to capture Fritz when Krista steps in and beheads him. •
Emily Hirst as Charlotte, a pureblood vampire and senior figure in the House of Chthon. She has journeyed to America to check on Marcus' progress with the Aurora Project. She has the appearance of a child and is often carried by her assistant, Thorne. •
Jody Thompson as Glynnis, a vampire ordered by Charlotte to investigate Marcus and the Aurora Project. She discovers that Marcus is misappropriating money and also that Krista is working for Blade. She interrupts Krista just after the latter has turned her own mother, and is ashed when Krista pierces her heart with a silver-backed mirror. •
Ryan Robbins as Sands, a vampire from the House of Erebus who had been captured by Marcus and used in the Aurora experiments. For reasons left unexplained, his scars never healed and he was left disfigured. Sands leads Blade to the testing facility, and in return Blade lets him go. Eventually, Sands finds his way to Damek and tells him what Marcus has been doing to the Armayan vampires. He is last seen getting into Damek's limousine. •
Bokeem Woodbine as
Steppin' Razor. A hardcore killer and the leader of the Bad Bloods street gang, he had taken Eric in after he ran away from his father. Blade had turned him into a vampire. — One night, Blade was overcome by the blood thirst and bit several gang members, turning them. Having been turned by the Daywalker, they were not accepted by any of the vampire houses. — In the main narrative, SR reappears years later and begins tracking down and killing people from Blade's past, in order to draw him out and take his revenge. He finds Blade's father and lures Blade to his childhood home for a final confrontation. •
John DeSantis as Thorne, Charlotte's
Lurch-like servant. He carries Charlotte around and attends to her every need. When he captures Chase and brings her to Charlotte, the latter tells Chase that Thorne only likes human women and has "quite an impressive collection". Thorne is habitually silent and only speaks in his final confrontation with Blade, to say "I want to hear you scream". • Scott Heindl as the White Prince, an insane rogue vampire, unaffiliated with any house. A serial killer who emerges every 19 years to kidnap and torture his victims, his face has been permanently scarred by silver. Shen and Blade get wind of him when his familiar kidnaps several girls from a night club. ==Production==