Blake gained acting experience with five years of work in
little theater productions. In 1953, she was in several productions at the
Pasadena Playhouse. she appeared on a number of television series, including the
syndicated Johnny Midnight,
Sheriff of Cochise, twice on
Rod Cameron's
State Trooper, and on the
David Janssen crime drama
Richard Diamond, Private Detective. Her first television appearance was on
NBC Matinee Theater. Blake was cast in
My Gun Is Quick, the film version of a
Mike Hammer novel by
Mickey Spillane. In 1957, she appeared in the first episode of
CBS's
Perry Mason, "
The Case of the Restless Redhead," in the title role of Evelyn Bagby, the defendant. In 1958, she again appeared in the title role as defendant Diana Reynolds in the episode "The Case of the Black-Eyed Blonde". Also in 1957, Blake played Lilli Bridgeman, who hires a professional assassin to murder her husband, Les (
Alan Hale Jr.), so she can marry a rival rancher, Kiley Rand (
Don Megowan), in the episode "Hired Gun" of the
ABC/
Warner Bros. Western series
Cheyenne, starring
Clint Walker. Blake played leading lady to
James Garner in "
The Day They Hanged Bret Maverick," the second-season opener in 1958 for the ABC/WB Western series,
Maverick. She appeared with
Claude Akins in two 1959 episodes, "Cattle Drive" and "Border Incident," of the CBS Western
The Texan, starring
Rory Calhoun. In 1959, Blake guest-starred in the first episode, "The Good Samaritan," of the syndicated Western series
Pony Express. That same year, her guest appearance in the short-lived series ''
The D.A.'s Man'' garnered her an
Emmy nomination. She appeared in a
Gunsmoke episode called "Wind" in March 1959 and one in 1973 called "A Game of Death...and of Life". Blake played a gambler's lady who tried to shoot Matt Dillon in the back. She also guest-starred on an episode of the detective series
77 Sunset Strip. Blake appeared in the 1959 film
-30-, with
Jack Webb, as a childless couple wanting to adopt a baby. The "-30-" comes from the symbol at the end of a newspaper story, as Webb played a newspaperman in the film. That year she also appeared as Ann Samuels in the first season of the series
Bonanza, episode 13, ″Vendetta″. In 1960, she played Callie Carter in the
Rawhide episode "Incident of the Murder Steer" (Season 2, Episode 28). Blake guest-starred on
Mike Connors' CBS detective series,
Tightrope; the CBS sitcom,
Pete and Gladys; and on the
NBC Western series,
Riverboat, starring
Darren McGavin; and
Overland Trail, with
William Bendix and
Doug McClure. She performed the lead female dramatic role on the
Route 66 TV series in a January 1960 episode (first season). She also guest-starred on police drama TV series
M Squad, starring
Lee Marvin (Season 3, Episode 25). In 1960, with Robert Lansing, she co-starred in an episode of the TV series
Thriller. Blake is best remembered for her portrayal of Dorothy Baxter, an interior designer and the wife of George Baxter (
Don DeFore), a lawyer, on the NBC sitcom
Hazel (1961). Following the show's cancellation by NBC in 1965, DeFore and Blake were dropped from the series when CBS picked up the show for one more season. They were replaced by
Ray Fulmer and
Lynn Borden, respectively, in the roles of Steve and Barbara Baxter, the younger brother and sister-in-law of George Baxter. After
Hazel, Blake guest-starred in an episode of the ABC Western series
The Legend of Jesse James. In 1966, she appeared in the episode "Nice Day for a Hanging" of
Chuck Connors' NBC Western series,
Branded. In 1968, she appeared in a final season episode of
The Andy Griffith Show as an attractive lawyer in Raleigh named Lee Drake, whom Sheriff Andy Taylor has to give a deposition to on a case in Mayberry involving a Raleigh resident. She guest-starred in a 1974 episode of
Cannon and in a 1978 episode of
Family, a series in which her daughter,
Meredith Baxter, co-starred. ==Later career==