Pérez began his career in his native Panama with
Panamá Viejo. He made his debut with the club in 1998 and went on to score 27 goals in 56 matches. In 2001, he joined
Árabe Unido and continued his goal scoring form. In 2002, he joined top Uruguayan side
Nacional. The following season, he left for Colombia signing with
Envigado, scoring a goal on his debut against
Independiente Medellin in the process. After one season at the club he joined
Centauros and went on to score 29 goals in 37 matches, catching the attention of one of Colombia's top clubs
Deportivo Cali. For the 2005 season he signed with Cali and remained at the club for two years in which he continued with his goal scoring form. In 2006 Perez joined
Cúcuta. With Cúcuta, Perez won the
Copa Mustang in 2006 against
Deportes Tolima. In 2007 Cúcuta and Blas Perez made their debut in
Copa Libertadores, in which Blas scored eight goals, including two against Argentina's
Boca Juniors. The eight goals were the second-most in the tournament. On 29 May 2007, Spanish
Segunda División team
Hércules CF signed
Super Ratón on a four-year contract in which they acquired 50% of the players rights. It was valued at US$2.7 million, with Blas Perez earning 60 thousand dollars per month. Perez enjoyed a brief stay in Spain in which he scored four goals in 16 matches. On 18 January 2008, he signed with
UANL Tigres, his seventh club in his career and first in Mexico. He played for
Pachuca for the
2009 Clausura in a loan deal after
Miguel Sabah's transfer to
Pachuca did not work out. He scored eight goals in 15 matches with Pachuca. After his impressive display in the
2009 CONCACAF Gold Cup,
Al Wasl FC of Dubai was able to secure Blas Pérez services to play in the
UAE League based on
Al Wasl's new coach
Alexandre Guimarães recommendation. He stayed there only for the first half of the
2009–10 season before moving back to Mexico to play for
San Luis. After having played 17 games in the
Torneo Bicentenario and 2 in the
2010 edition of the
Copa Libertadores and having scored 5 goals in both tournaments, he was released at the end of the season. He was later signed by
Club León from the
Liga de Ascenso in the 2010 edition of the Mexican draft. he rediscovered his goal scoring form with Club León with 19 goals in 28 matches. For the second half of the 2011 season he was again sent on loan this time to
Indios. For the 2012
Major League Soccer season, he signed with
FC Dallas. On 2 December 2015, it was announced that FC Dallas would not be renewing Perez's contract. On 16 February 2016, Perez was traded to
Vancouver Whitecaps FC for
Mauro Rosales. At the conclusion of the 2016 season Perez's contract was not renewed. On 31 January 2017, Pérez signed with Panamanian club,
C.D. Árabe Unido. On 25 November 2018, Pérez retired from playing professional football. He came out of retirement in 2022, however, to play arena soccer with the Dallas Sidekicks of the Major Arena Soccer League. Perez was nominated for the league's Newcomer of the Year honor. In June 2024, it was announced that Pérez had re-signed for the 2024–25 season. ==International career==