Born in
New Rochelle, New York, Perciasepe was raised in
Brewster, New York and later
Ancram, New York. He attended Immaculate High School in
Danbury, Connecticut, graduating in 1969. In 1974 he graduated from
Cornell University with a
Bachelor of Science in natural resources and in 1976 received his
Master's Degree in Planning and Public Administration from the
Maxwell School of Citizenship and Public Affairs at
Syracuse University. After graduation, Perciasepe began working in the
Baltimore City Planning Department (1976–80), where he later served as Chief of Capital Planning (1980–86) and as Assistant Director for Planning (1986–87). In 1987, Perciasepe joined the
Maryland Department of the Environment (MDE), serving as Assistant Secretary of Planning and Capital Programs until 1989, when he was appointed Deputy Secretary of the full Department by then
Maryland Governor William Donald Schaefer. In 1987, Governor Schaefer appointed Martin Walsh as the first Secretary of the Environment. After Governor Schaefer was
re-elected in 1990, he announced that he would "reorganize his administration," appointing Perciasepe to be Walsh's replacement as Maryland's Secretary of the Environment, thus making Perciasepe the second Secretary of MDE. During his tenure as Secretary of the Environment, Perciasepe oversaw the agency's $59 million budget and 770 employees. While there, he took actions that included re-evaluating the
Chesapeake Bay Program's efforts to reduce harmful nutrients, chairing the
Northeast Ozone Transport Commission for cleaner regional air quality, reducing emissions from cars, and initiating new recycling requirements. ==Early EPA career==