Canton Charge (2018–2019) On September 18, 2018, Colson signed with the
Cleveland Cavaliers. On October 13, he was waived by the Cavaliers, but was added to the roster of the Cavs'
NBA G League affiliate, the
Canton Charge. In his first G League game, a 101–89 loss to the
Wisconsin Herd, Colson led the team with 23 points and 15 rebounds, shooting 10-of-18 from the floor. For the G League team, in 23 games he averaged 15.5 points, 7.8 rebounds, and 1.5 blocks per game.
Milwaukee Bucks (2019) On January 15, 2019, Colson was signed to a
two-way contract by the
Milwaukee Bucks. Under the terms of the deal, he split time with the Bucks' G League affiliate, the
Wisconsin Herd. For the G League team, in 23 games he averaged 14.3 points, 6.0 rebounds, and 0.8 blocks per game. On March 31, Colson started his first NBA game against the
Atlanta Hawks and in that game, he managed to score 15 points and grabbed 16 rebounds in 41 minutes of playing time. On July 21, 2019, Colson was waived by the Bucks.
Darüşşafaka (2019–2020) On July 30, 2019, Colson signed with
Darüşşafaka. Colson and the team mutually parted ways on April 24, 2020. Colson averaged 12.2 points and 5.1 rebounds per game in the Turkish League and 10.8 points and 5.0 rebounds in
EuroCup play.
SIG Strasbourg (2020–2021) On August 31, 2020, Colson signed with
SIG Strasbourg. He was named player of the week on October 14, after posting 24 points, nine rebounds and two assists in a win against
Orléans Loiret Basket. In 49 games he averaged 18.1 points, 5.3 rebounds, and 0.6 blocks per game. He was selected
Most Valuable Player for the regular season of
2020–21 Basketball Champions League.
Pınar Karşıyaka (2021–2022) On July 10, 2021, Colson signed with
Pınar Karşıyaka of the
Turkish Super League In 42 games he averaged 15.9 points, 7.2 rebounds, and 0.8 blocks per game.
Fenerbahçe (2024–present) in 2024 On June 28, 2024, Colson signed a three-year deal with Turkish powerhouse
Fenerbahçe Beko. On May 25, 2025, he helped Fenerbahçe to their second EuroLeague championship in
Abu Dhabi. ==Playing style==