On January 14, 1979, DeSimone's wife, Angela, reported him missing. She said she had last seen DeSimone a few weeks earlier when he borrowed $60 from her. It is believed that DeSimone was murdered as revenge for the two unsanctioned murders of John Gotti's men, Bentvena and Jerothe. Another theory is that DeSimone eventually became suspected of being a police informant and was killed by Jimmy Burke. When Hill became an
FBI informant in 1980, he told authorities that DeSimone had been murdered by the Gambino family. Despite the oft-given date of death of January 14, 1979, the exact date of DeSimone's murder is uncertain. Hill claimed that in "the week after Christmas", he and Burke had gone to Florida to straighten out a drug deal gone bad. DeSimone had remained behind in New York, having been told in late December 1978 or early January 1979 that he was going to be
made. Two theories about DeSimone's alleged murderers exist from mob insiders. According to mob informant Joseph "Joe Dogs" Iannuzzi, Thomas Agro claimed in 1985 that he had murdered DeSimone, as well as his brother Anthony after he turned informant. Agro also suggested murdering the eldest and last remaining brother, Robert. According to Ianuzzi, Agro would often laughingly refer to killing the third DeSimone brother, stating: "Maybe it's time to go for the DeSimone trifecta!" Another account, told by Hill in
Gangsters and Goodfellas, states that Gotti himself was the assassin, although in the presence of Agro. On May 17, 2007, episode of
The Howard Stern Show, Hill reaffirmed that Gotti had killed DeSimone. He also added that the death "took a long time", as Bentvena had been a personal friend of Gotti's, and he wanted DeSimone to suffer before he died. Gotti's role as the assassin was repeated in the 2015 book
The Lufthansa Heist, co-written by Hill and journalist Daniel Simone, It has been theorized DeSimone is buried in
The Hole, a suspected "Mafia graveyard" on the Brooklyn-Queens border near Kennedy airport, where the body of
Al Indelicato was found in 1981 and where the bodies of
Philip Giaccone and
Dominick Trinchera were recovered by police in 2004. ==Portrayal in film==