2-Methyl-AP-237 has been sold on the grey market as a
designer opioid, first identified by a police forensic laboratory in Slovenia in March 2019. In 2023, the
United States Department of Justice took criminal action against two individuals for selling 2-Methyl-AP-237 under the false pretenses that such product was intended for
'research purposes' only. One of the pair was sentenced to five years in
federal prison. The
WHO and the
Ministry of Social Affairs, Health, Care and Consumer Protection have published reports on 2-Methyl-AP-237. According to their analysis, it is a little bit less potent than
fentanyl and can be reversed using
naltrexone. There haven't been any studies on its systemic toxicity but there have been overdose deaths linked to it, most in
combination with other drugs. It is primarily consumed orally or through snorting. While the methyl substitution creates a
stereocenter, the drug is sold as the
racemat. ] ==See also==