Prelude In 1568, Ayutthaya king
Maha Chakkraphat requested King
Setthathirath of
Lan Xang to attack Phitsanulok, ploying to arrest its King
Mahathammarachathirat. When Mahathammarachathirat asked Ayutthaya for assistance Maha Chakkraphat dispatched general Phya Siharat–Dejo, tasking him with detaining Mahathammarachathirat. Siharat–Dejo instead remained in Phitsanulok and disclosed Maha Chakkraphat's true intentions, pushing Burma into an armed intervention.
Siege of Phitsanulok in 1887. A Burmese force broke through the Lao lines and joined the defenders of Phitsanulok which was besieged at the time. In the meantime, an Ayutthayan army advanced on Phitsanulok under the guise of reinforcements. Upon their arrival the Ayutthayans were asked to stay outside the city, on the same night the Phitsanulokans launched flaming rafts on the Ayutthayan fleet, destroying it. The losses prompted both the Lao and Ayutthayans to break the siege and retreat, the Lao troops later ambushed and annihilated a Burmese force that attempted to chase them. During the course of his retreat, Maha Chakkraphat unsuccessfully attacked Kamphaeng Phet. His plans changed however when he learned that Mahathammarachathirat was on an official visit to Burma, causing him to return to Phitsanulok. The Ayutthayans then proceeded to kidnap all of Mahathammarachathirat's family but his son Prince
Naresuan who was accompanying his father. The kidnapping was to dissuade Phitsanulok from launching counter-attacks on Ayutthaya, nonetheless this act led the Burmese to initiate a joint invasion of Ayutthaya with the help of their Thai puppet states. Having gained the support of northern Thai states,
Bayinnaung amassed five armies that consisted of 54,600 men, 5,300 horses, and 530 elephants according to Burmese sources. Thai sources mention an army consisting of 546,000 infantrymen and 53,000 in cavalry, however, that was likely an exaggeration. The Burmese marched from the north until encountering a Lao army at the Pa Sak Valley near
Phetchabun. The Lan Xang forces prevailed at which point one of the commanding generals from
Nakhon Phanom broke south toward Ayutthaya. The Burmese rallied and were able to destroy the divided forces, and King Setthathirath had to retreat toward
Vientiane. ==Siege of Ayutthaya and Vientiane==