Mildred Thompson was known for her political involvement, like supporting women's rights by participating in the
women's suffrage parade in New York with
Lucy Maynard Salmon in 1911. As she was a close friend to Eleanor Roosevelt, Thompson was active in politics during the
Franklin D. Roosevelt administration. She was the chairman of the woman's division of the Democratic National Committee and head of the educator's committee during FDR's 1936 campaign for re-election. Thompson campaigned for Roosevelt in the years 1936, 1940, and 1944. In 1944, Thompson was appointed by the state department as the only woman representative to help represent
CAME or Conference of Allied Ministers of Education in London, working with Commissioner of Education, John W. Studebaker, and Representative J. William Fulbright of Arkansas. == Personal life and death ==