Preliminary round The preliminary round first legs were played on 15–17 February, and the second legs were played on 29 February-2 March 2008.
4 Byes:
ASEC Mimosas,
Etoile du Sahel,
JS Kabylie,
Al Ittihad,
Al Ahly, and
Al Hilal. 1
Invincible Eleven withdrew. 2 CAF ordered that the tie was to be played over one leg in Kinshasa due to the civil war in Chad, but
Renaissance FC objected to the ruling and refused to travel; they were ejected from the competition, fined $4000 and banned from CAF competitions for three years. 3
Tusker FC were ejected from the competition and fined $5000 after Kenyan immigration officials refused the appointed match officials for the first leg entry into the country. 4
Wallidan FC and
FC Civics withdrew before the draw.
Note: Clubs from the
Central African Republic,
Djibouti,
Kenya,
Liberia,
Malawi,
São Tomé and Príncipe,
Sierra Leone and
Somalia all had their entries rejected for failure to fulfil their financial obligations.
First round The 1/16 Finals first leg matches were played on 21–23 March and the second legs were played on 4–6 April 2008. 1
Al Tahrir withdrew due to internal dissent.
Second round The 1/8 Finals first legs were played on 25–27 April and the second legs were played on 9–11 May 2008. ==Group stage==