Inedible parts of the plant, such as the leaves, stems, roots, seeds and unripe fruits, can be toxic due to the presence of
cyanogenic glycosides and
alkaloids. Traditional methods of consuming elderberry includes jams, jellies, and syrups, all of which cook down the fruit and strain out the seeds. Unpublished research may show that
S. canadensis (American elderberry) has lower cyanide levels than apple juice, and that its fruit does not contain enough beta-glucosidase (which convert glucosides into cyanide) to create cyanide within that biochemical pathway. For comparison, assuming
S. nigra has levels of no more than 25 micrograms of cyanogenic glycosides/milligram of berry weight, assuming all of the glycosides were converted to cyanide, and assuming a toxicity of 50 mg for a 50 kg vertebrate, one would need to eat 2 kilograms (~4.4 pounds) of berries in one sitting to reach the lower limits of lethal toxicity (1 mg cyanide/kg of weight). For the upper limits (3 mg/kg), one would need to eat 6 kg or ~13 pounds. ==Uses==