The Upper School consists of students from Grades 6 to 12, with a current enrollment of just over 1,000 students, making up almost 45% of the student body. Students in Grades 6–10 take part in the Middle Years Program (MYP), while students in Grade 11–12 take part in the
Diploma Program (DP). The Principal of the Upper School is Dr. David Butler. Starting in August 2020, CDNIS began the Middle Years Program (MYP) in Grade 6. CDNIS has one of the largest DP cohorts in Hong Kong. 99% of the 103 students in the Class of 2024, the 14th cohort of IB graduates, were awarded the IB Diploma. Two students were awarded a maximum of 45 points out of 45, while 43 students achieved a score of 40 or above. The Class of 2024 IB score average was 38 points. ==History==