As a professional he had 58 fights (47–3–8), from 1985 to 1998. He campaigned at the flyweight and super flyweight divisions, winning world titles in both. After 3 unsuccessful attempts at the world title, Salazar became the
IBF World super flyweight champion when he beat
Harold Grey in 1995. He would defend the title once before losing it to the same Harold Grey. After that he decided to move down to flyweight and campaign for the
WBO World title, winning it against
Alberto Jiménez. He defended that title 5 times before losing it to
Rubén Sánchez León in controversial fashion as he cited he was hit after the referee had stopped actions and the punch caused him a broken jaw. Salazar decided to retire from boxing after the fight citing medical issues. ==Professional boxing record==