4:["$","div",null,{"className":"min-h-screen bg-white flex flex-col","children":[["$","div",null,{"className":"px-6 pt-6 pb-4 border-b border-gray-100","children":[["$","div",null,{"className":"flex items-center gap-1.5 text-xs text-gray-400 mb-4","children":[["$","a",null,{"href":"/","className":"hover:text-[#26a69a] transition-colors","children":"Market"}],["$","span",null,{"children":"›"}],["$","span",null,{"className":"text-gray-600","children":"Caseous necrosis"}]]}],["$","div",null,{"className":"text-[10px] text-gray-400 uppercase tracking-widest mb-1","children":"Company Profile"}],["$","h1",null,{"className":"text-2xl font-bold text-gray-900","children":"Caseous necrosis"}],null]}],["$","div",null,{"className":"flex-1 px-6 py-6","children":[["$","p",null,{"className":"text-sm text-gray-600 leading-relaxed mb-8","children":"Caseous necrosis or caseous degeneration is a unique form of cell death in which the tissue maintains a cheese-like appearance, appearing as a soft and white proteinaceous dead cell mass. The dead tissue is enclosed within a granuloma, and differs from coagulative necrosis in that tissue structure is destroyed. Caseous necrosis is most notably associated with tuberculoma."}],["$","div",null,{"className":"columns-1 md:columns-2 gap-10","children":[["$","div","0",{"className":"mb-8 break-inside-avoid","children":[["$","div",null,{"className":"text-xs font-semibold text-gray-400 uppercase tracking-wide mb-3 border-b border-gray-100 pb-1","children":"Histology"}],["$","div",null,{"className":"text-sm text-gray-600 leading-relaxed wiki-content","dangerouslySetInnerHTML":{"__html":"In caseous necrosis no histological architecture is preserved (unlike with coagulative necrosis). On microscopic examination with H&E staining, the area is acellular, characterised by amorphous, roughly granular eosinophilic debris of dead cells, ==Causes=="}}]]}],["$","div","1",{"className":"mb-8 break-inside-avoid","children":[["$","div",null,{"className":"text-xs font-semibold text-gray-400 uppercase tracking-wide mb-3 border-b border-gray-100 pb-1","children":"Causes"}],["$","div",null,{"className":"text-sm text-gray-600 leading-relaxed wiki-content","dangerouslySetInnerHTML":{"__html":"Caseous necrosis is characteristically associated with tuberculomas. ==Pathophysiology=="}}]]}],["$","div","2",{"className":"mb-8 break-inside-avoid","children":[["$","div",null,{"className":"text-xs font-semibold text-gray-400 uppercase tracking-wide mb-3 border-b border-gray-100 pb-1","children":"Pathophysiology"}],["$","div",null,{"className":"text-sm text-gray-600 leading-relaxed wiki-content","dangerouslySetInnerHTML":{"__html":"The process begins as infection is recognized by the body and macrophages begin walling off the microorganisms or pathogens. As macrophages release chemicals that digest cells the cells begin to die. As the cells die they disintegrate but are not completely digested and the debris of the disintegrated cells clumps together creating soft granular mass that has the appearance of cheese. Some data suggests that host macrophages associated with granulomas may prevent effective immune clearance of mycobacteria, due to their epithelioid morphology and associated barrier function. == References =="}}]]}]]}],["$","div",null,{"className":"mt-8 pt-4 border-t border-gray-100","children":["$","a",null,{"href":"https://en.wikipedia.org/wiki/Caseous%20necrosis","target":"_blank","rel":"noopener noreferrer","className":"text-xs text-gray-400 hover:text-gray-600 transition-colors","children":"Source: Wikipedia ↗"}]}]]}],"$Lf"]}]