, 2019 Desantis became
first lady of Florida on January 8, 2019, when her husband,
Ron DeSantis, became the 46th
governor of Florida. In February 2019, DeSantis established the First Lady's Medal for Courage, Commitment, and Service. Soon after, she announced Florida's 2019
Black History Month theme as "Celebrating Public Service" where she and the governor honored the winners of Florida's Black History Month student contests and Excellence in Education Award recipients at the
Governor's Mansion. DeSantis recognized Mary Ann Carroll, the only female member of
the Highwaymen, as Florida's featured artist for the month. DeSantis participated in a Recovery Redfish Release to address the impacts of
red tide. "I've heard from those throughout Florida who understand that our water must be safe for our families, visitors and economy." DeSantis has hosted listening sessions on
Venezuela,
hurricane relief, and
mental health. During the
COVID-19 pandemic, she and her husband held a roundtable in August 2020 centered on the mental health impact of the pandemic. According to
Politico, DeSantis has taken on a "sort of policy portfolio of her own that ranges from hurricane recovery to issues of mental health" in her role as First Lady.
Hope Florida scandal In 2021, DeSantis founded
Hope Florida, a charity to connect underprivileged Floridians with government resources, nonprofits, the private sector and religious organizations. In early 2025, the
Florida House of Representatives launched an investigation into Hope Florida, in particular a transaction in which the foundation received $10 million of the $67 million legal settlement between
Centene and
Florida Agency for Health Care Administration. Hope Florida diverted the settlement proceeds to Secure Florida's Future and Save our Society from Drugs. == Political activity ==