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Catabolite activator protein

In cell biology, catabolite activator protein (CAP), which is also known as cAMP receptor protein (CRP), is a trans-acting transcriptional activator in bacteria that effectively catalyzes the initiation of DNA transcription by interacting with RNA polymerase in a way that causes the DNA to bend.

CAP's role in the catabolism of saccharides
One example of the role of CAP is its criticality in activating the ability of E. coli to metabolize lactose. The cAMP-CAP complex allows RNA polymerase to bind to the lac operon and transcribe its genes, which encode the proteins required for breaking down lactose into glucose and galactose. controlling the expression of malT, a gene critical in the uptake and metabolism of maltodextrins. == References ==
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