The district has as its basis the 1905 formation of the Inglewood Union High School District, which included at the outset the territories of
Hawthorne,
Inglewood,
Lennox, and
Wiseburn school districts. In 1912 the
El Segundo school district formed out of territory in the Wiseburn district and was a part of the Inglewood high school district. El Segundo withdrew from CVUHSD on November 22, 1925, when the
El Segundo Unified School District was formed. The high school district was named Centinela Valley Union High School District on November 1, 1944. On July 1, 1954, Inglewood, with its
Inglewood and
Morningside high schools, withdrew to form the
Inglewood Unified School District. Cheryl M. White became the superintendent in 2004. Jose Fernandez became the superintendent in 2008. He received $663,000 in total compensation in 2013. This fact was revealed in a 2014 newspaper investigation. The superintendent of the
Los Angeles Unified School District,
John Deasy, had an annual salary of $390,000.
KCAL-TV stated that a crowd appeared asking for Fernandez to resign. Fernandez stated that he had made improvements to CVUSD. The board later put Fernandez on paid leave and selected Bob Cox as the interim superintendent. The District Attorney of Los Angeles County began investigating the district. In 2014 the
Daily Breeze reported that
TELACU, a company which received building contracts worth millions of US dollars from the high school district, had bankrolled election campaigns of board members. In 2014 the Wiseburn Elementary School district unified and became the Wiseburn USD, and so its area left the Centinela Valley high school district. In 2021 a block of unincorporated areas that was in the Lawndale School District and Centinela Valley USD voted on a proposal on whether it should move to Wiseburn USD; previously students living in the block living in Wiseburn would have had to get permission from their zoned school districts to attend Wiseburn. According to Hunter Lee the
Daily Breeze, "few" people voted in the election. The vote to transfer the area to Wiseburn was approved. ==Administration==